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BMCBI
2006
101views more  BMCBI 2006»
15 years 6 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe
BMCBI
2006
200views more  BMCBI 2006»
15 years 6 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
BMCBI
2006
109views more  BMCBI 2006»
15 years 6 months ago
iHOPerator: user-scripting a personalized bioinformatics Web, starting with the iHOP website
Background: User-scripts are programs stored in Web browsers that can manipulate the content of websites prior to display in the browser. They provide a novel mechanism by which u...
Benjamin M. Good, Edward A. Kawas, Byron Yu-Lin Ku...
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal
BMCBI
2006
147views more  BMCBI 2006»
15 years 6 months ago
Grouping Gene Ontology terms to improve the assessment of gene set enrichment in microarray data
Background: Gene Ontology (GO) terms are often used to assess the results of microarray experiments. The most common way to do this is to perform Fisher's exact tests to find...
Alex Lewin, Ian C. Grieve