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BMCBI
2006
128views more  BMCBI 2006»
15 years 6 months ago
Lexical adaptation of link grammar to the biomedical sublanguage: a comparative evaluation of three approaches
Background: We study the adaptation of Link Grammar Parser to the biomedical sublanguage with a focus on domain terms not found in a general parser lexicon. Using two biomedical c...
Sampo Pyysalo, Tapio Salakoski, Sophie Aubin, Adel...
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
Projections for fast protein structure retrieval
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
BMCBI
2006
124views more  BMCBI 2006»
15 years 6 months ago
Network-based de-noising improves prediction from microarray data
Background: Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as...
Tsuyoshi Kato, Yukio Murata, Koh Miura, Kiyoshi As...
BMCBI
2006
94views more  BMCBI 2006»
15 years 6 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
Discrete profile comparison using information bottleneck
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...