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BMCBI
2006
15 years 6 months ago
2006
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
152
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BMCBI
2006
15 years 6 months ago
2006
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
151
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BMCBI
2006
15 years 6 months ago
2006
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
151
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BMCBI
2006
15 years 6 months ago
2006
Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
144
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BMCBI
2006
2006
On single and multiple models of protein families for the detection of remote sequence relationships
15 years 6 months ago
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...