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BMCBI
2006
15 years 6 months ago
2006
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
181
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BMCBI
2006
15 years 6 months ago
2006
Background: Proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, as mass spectrometry data are high-dimen...
195
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BMCBI
2006
15 years 6 months ago
2006
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
172
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BMCBI
2006
15 years 6 months ago
2006
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
164
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BMCBI
2006
15 years 6 months ago
2006
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...