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BMCBI
2006
165views more  BMCBI 2006»
15 years 6 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2006
91views more  BMCBI 2006»
15 years 6 months ago
Empirical study of supervised gene screening
Background: Microarray studies provide a way of linking variations of phenotypes with their genetic causations. Constructing predictive models using high dimensional microarray me...
Shuangge Ma
BMCBI
2006
104views more  BMCBI 2006»
15 years 6 months ago
Semi-supervised discovery of differential genes
Background: Various statistical scores have been proposed for evaluating the significance of genes that may exhibit differential expression between two or more controlled conditio...
Shigeyuki Oba, Shin Ishii
BMCBI
2006
242views more  BMCBI 2006»
15 years 6 months ago
Predicting residue-wise contact orders in proteins by support vector regression
Background: The residue-wise contact order (RWCO) describes the sequence separations between the residues of interest and its contacting residues in a protein sequence. It is a ne...
Jiangning Song, Kevin Burrage
BMCBI
2006
205views more  BMCBI 2006»
15 years 6 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch