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169
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BMCBI
2010
15 years 7 months ago
2010
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
174
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BMCBI
2010
15 years 7 months ago
2010
Background: The reconstruction of protein complexes from the physical interactome of organisms serves as a building block towards understanding the higher level organization of th...
208
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BMCBI
2010
15 years 7 months ago
2010
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
198
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BMCBI
2010
15 years 7 months ago
2010
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
181
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BMCBI
2010
15 years 7 months ago
2010
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...