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TC
2010
15 years 5 months ago
Network-on-Chip Hardware Accelerators for Biological Sequence Alignment
—The most pervasive compute operation carried out in almost all bioinformatics applications is pairwise sequence homology detection (or sequence alignment). Due to exponentially ...
Souradip Sarkar, Gaurav Ramesh Kulkarni, Partha Pr...
CPM
2006
Springer
112views Combinatorics» more  CPM 2006»
15 years 10 months ago
Local Alignment of RNA Sequences with Arbitrary Scoring Schemes
Abstract. Local similarity is an important tool in comparative analysis of biological sequences, and is therefore well studied. In particular, the Smith-Waterman technique and its ...
Rolf Backofen, Danny Hermelin, Gad M. Landau, Oren...
BMCBI
2008
143views more  BMCBI 2008»
15 years 7 months ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton
BMCBI
2010
110views more  BMCBI 2010»
15 years 7 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
BMCBI
2006
153views more  BMCBI 2006»
15 years 6 months ago
The 3of5 web application for complex and comprehensive pattern matching in protein sequences
Background: The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variabl...
Markus Seiler, Alexander Mehrle, Annemarie Poustka...