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NAR
2000
120views more  NAR 2000»
15 years 6 months ago
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions bas...
Ross A. Overbeek, Niels Larsen, Gordon D. Pusch, M...
CORR
2012
Springer
183views Education» more  CORR 2012»
14 years 2 months ago
Twisting q-holonomic sequences by complex roots of unity
A sequence fn(q) is q-holonomic if it satisfies a nontrivial linear recurrence with coefficients polynomials in q and qn . Our main theorem states that q-holonomicity is preserve...
Stavros Garoufalidis, Christoph Koutschan
BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
A method for automatically extracting infectious disease-related primers and probes from the literature
Background: Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the ...
Miguel García-Remesal, Alejandro Cuevas, Vi...
BMCBI
2007
89views more  BMCBI 2007»
15 years 6 months ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
PVLDB
2008
107views more  PVLDB 2008»
15 years 6 months ago
Finding relevant patterns in bursty sequences
Sequence data is ubiquitous and finding frequent sequences in a large database is one of the most common problems when analyzing sequence data. Unfortunately many sources of seque...
Alexander Lachmann, Mirek Riedewald