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JCB
2008
75views more  JCB 2008»
15 years 6 months ago
New, Improved, and Practical k-Stem Sequence Similarity Measures for Probe Design
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...
Anthony J. Macula, Alexander Schliep, Morgan A. Bi...
NAR
2006
107views more  NAR 2006»
15 years 6 months ago
CorGen - measuring and generating long-range correlations for DNA sequence analysis
CorGen is a web server that measures long-range correlations in the base composition of DNA and generates random sequences with the same correlation parameters. Long-range correla...
Philipp W. Messer, Peter F. Arndt
ALIFE
2005
15 years 6 months ago
Evolution of DNA Uptake Signal Sequences
The DNA of some naturally competent species of bacteria contains a large number of evenly distributed copies of a short sequence. This highly overrepresented sequence is believed t...
Dominique Chu, Hoong-Chien Lee, Tom Lenaerts
COMPGEOM
2011
ACM
14 years 10 months ago
On the structure and composition of forbidden sequences, with geometric applications
Forbidden substructure theorems have proved to be among of the most versatile tools in bounding the complexity of geometric objects and the running time of geometric algorithms. T...
Seth Pettie
BMCBI
2007
159views more  BMCBI 2007»
15 years 6 months ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...