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INFORMS
2010
125views more  INFORMS 2010»
15 years 4 months ago
Combining Exact and Heuristic Approaches for the Capacitated Fixed-Charge Network Flow Problem
We develop a solution approach for the fixed charge network flow problem (FCNF) that produces provably high-quality solutions quickly. The solution approach combines mathematica...
Mike Hewitt, George L. Nemhauser, Martin W. P. Sav...
BMCBI
2010
140views more  BMCBI 2010»
15 years 3 months ago
An improved machine learning protocol for the identification of correct Sequest search results
Background: Mass spectrometry has become a standard method by which the proteomic profile of cell or tissue samples is characterized. To fully take advantage of tandem mass spectr...
Morten Kallberg, Hui Lu
CPAIOR
2008
Springer
15 years 8 months ago
Fitness-Distance Correlation and Solution-Guided Multi-point Constructive Search for CSPs
Solution-Guided Multi-Point Constructive Search (SGMPCS) is a complete, constructive search technique that has been shown to out-perform standard constructive search techniques on ...
Ivan Heckman, J. Christopher Beck
EVOW
2008
Springer
15 years 8 months ago
Reactive Stochastic Local Search Algorithms for the Genomic Median Problem
Abstract. The genomic median problem is an optimization problem inspired by a biological issue: it aims at finding the chromosome organization of the common ancestor to multiple li...
Renaud Lenne, Christine Solnon, Thomas Stützl...
EC
2008
146views ECommerce» more  EC 2008»
15 years 6 months ago
Automated Discovery of Local Search Heuristics for Satisfiability Testing
The development of successful metaheuristic algorithms such as local search for a difficult problems such as satisfiability testing (SAT) is a challenging task. We investigate an ...
Alex S. Fukunaga