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BMCBI
2006
182views more  BMCBI 2006»
15 years 6 months ago
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
BMCBI
2006
143views more  BMCBI 2006»
15 years 6 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
92views more  BMCBI 2006»
15 years 6 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Gene analogue finder: a GRID solution for finding functionally analogous gene products
Background: To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in a...
Angelica Tulipano, Giacinto Donvito, Flavio Licciu...