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FCCM
2009
IEEE
169views VLSI» more  FCCM 2009»
16 years 28 days ago
RC-BLASTn: Implementation and Evaluation of the BLASTn Scan Function
BLASTn is a tool universally used by biologists to identify similarities between nucleotide based biological genome sequences. This report describes an FPGA based hardware impleme...
Siddhartha Datta, Parag Beeraka, Ron Sass
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
15 years 6 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
BMCBI
2006
92views more  BMCBI 2006»
15 years 6 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2006
131views more  BMCBI 2006»
15 years 6 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...
BMCBI
2007
136views more  BMCBI 2007»
15 years 6 months ago
Comparison of protein structures by growing neighborhood alignments
Background: Design of protein structure comparison algorithm is an important research issue, having far reaching implications. In this article, we describe a protein structure com...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...