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BMCBI
2011
15 years 1 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
JCB
2007
146views more  JCB 2007»
15 years 6 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
SMI
2003
IEEE
172views Image Analysis» more  SMI 2003»
15 years 11 months ago
Skeleton Based Shape Matching and Retrieval
In this paper, we describe a novel method for searching and comparing 3D objects. The method encodes the geometric and topological information in the form of a skeletal graph and ...
H. Sundar, Deborah Silver, Nikhil Gagvani, Sven J....
BMCBI
2006
153views more  BMCBI 2006»
15 years 6 months ago
The 3of5 web application for complex and comprehensive pattern matching in protein sequences
Background: The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variabl...
Markus Seiler, Alexander Mehrle, Annemarie Poustka...
CCGRID
2005
IEEE
15 years 8 months ago
A semantic grid-based data access and integration service for bioinformatics
Given the heterogeneous nature of biological data and their intensive use in many tools, in this paper we propose a semantic data access and integration (DAI) service, based on th...
Giovanni Aloisio, Massimo Cafaro, Italo Epicoco, S...