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189
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BMCBI
2008
15 years 6 months ago
2008
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
163
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BMCBI
2007
15 years 6 months ago
2007
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
149
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BMCBI
2008
2008
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
15 years 6 months ago
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
220
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BMCBI
2008
15 years 6 months ago
2008
Complexity of post-genomic data and multiplicity of mining strategies are two limits to Knowledge Discovery in Databases (KDD) in life sciences. Because they provide a semantic fr...
181
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BMCBI
2008
15 years 6 months ago
2008
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...