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BMCBI
2010
189views more  BMCBI 2010»
15 years 6 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2010
89views more  BMCBI 2010»
15 years 6 months ago
Leukocyte Nucleus Segmentation and Nucleus Lobe Counting
Background: Leukocytes play an important role in the human immune system. The family of leukocytes is comprised of lymphocytes, monocytes, eosinophils, basophils, and neutrophils....
Yung-Kuan Chan, Meng-Hsiun Tsai, Der-Chen Huang, Z...
BMCBI
2007
185views more  BMCBI 2007»
15 years 6 months ago
GEDI: a user-friendly toolbox for analysis of large-scale gene expression data
Background: Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, a...
André Fujita, João Ricardo Sato, Car...
BMCBI
2007
146views more  BMCBI 2007»
15 years 6 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
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