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200
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BMCBI
2010
15 years 6 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
170
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BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
15 years 6 months ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
198
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BMCBI
2008
15 years 6 months ago
2008
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
185
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BMCBI
2007
15 years 6 months ago
2007
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
172
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BMCBI
2010
15 years 6 months ago
2010
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...