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ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
15 years 5 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
TCAD
2011
15 years 28 days ago
GRIP: Global Routing via Integer Programming
Abstract—This work introduces GRIP, a global routing technique via integer programming. GRIP optimizes wirelength and via cost directly without going through a traditional layer ...
Tai-Hsuan Wu, Azadeh Davoodi, Jeffrey T. Linderoth
CORR
2012
Springer
232views Education» more  CORR 2012»
14 years 1 months ago
A Formal Comparison of Approaches to Datatype-Generic Programming
-generic programming increases program abstraction and reuse by making functions operate uniformly across different types. Many approaches to generic programming have been proposed...
José Pedro Magalhães, Andres Lö...
ICDE
2012
IEEE
249views Database» more  ICDE 2012»
13 years 8 months ago
Answering Why-not Questions on Top-k Queries
Abstract—After decades of effort working on database performance, the quality and the usability of database systems have received more attention in recent years. In particular, t...
Zhian He, Eric Lo
MICCAI
2007
Springer
16 years 7 months ago
Adaptive Metamorphs Model for 3D Medical Image Segmentation
Abstract. In this paper, we introduce an adaptive model-based segmentation framework, in which edge and region information are integrated and used adaptively while a solid model de...
Junzhou Huang, Xiaolei Huang, Dimitris N. Metaxas,...