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BMCBI
2011
15 years 1 months ago
SNPPicker: High quality tag SNP selection across multiple populations
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
Hugues Sicotte, David N. Rider, Gregory A. Poland,...
BMCBI
2011
15 years 1 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
BMCBI
2011
15 years 1 months ago
Properties of Metabolic Graphs: Biological Organization or Representation Artifacts?
Background: Standard graphs, where each edge links two nodes, have been extensively used to represent the connectivity of metabolic networks. It is based on this representation th...
Wanding Zhou, Luay Nakhleh
BMCBI
2011
15 years 1 months ago
SNiPlay: a web-based tool for detection, management and analysis of SNPs. Application to grapevine diversity projects
Background: High-throughput re-sequencing, new genotyping technologies and the availability of reference genomes allow the extensive characterization of Single Nucleotide Polymorp...
Alexis Dereeper, Stéphane Nicolas, Loic Le ...
BMCBI
2011
15 years 1 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
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