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157
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BMCBI
2010
15 years 6 months ago
2010
Background: With the growing amount of biomedical data available in public databases it has become increasingly important to annotate data in a consistent way in order to allow ea...
146
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BMCBI
2010
15 years 6 months ago
2010
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
187
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BMCBI
2010
15 years 6 months ago
2010
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
154
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BMCBI
2010
15 years 6 months ago
2010
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
171
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BMCBI
2010
15 years 6 months ago
2010
Background: Many high-throughput genomic experiments, such as Synthetic Genetic Array and yeast two-hybrid, use colony growth on solid media as a screen metric. These experiments ...