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BMCBI
2010
125views more  BMCBI 2010»
15 years 6 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach
Background: Developing and evaluating new technology that enables researchers to recover gene-expression levels of colonic cells from fecal samples could be key to a non-invasive ...
Nysia I. George, Joanne R. Lupton, Nancy D. Turner...
BMCBI
2006
155views more  BMCBI 2006»
15 years 6 months ago
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Anne-Mette K. Hein, Sylvia Richardson
IJSEKE
2006
99views more  IJSEKE 2006»
15 years 6 months ago
Weaving Deployment Aspects into Domain-specific Models
pecific models increase the level of abstraction used to develop large-scale component-based systems. Model-driven development (MDD) approaches (e.g., ModelIntegrated Computing and...
Krishnakumar Balasubramanian, Aniruddha S. Gokhale...
TOMACS
2010
182views more  TOMACS 2010»
15 years 4 months ago
State-dependent importance sampling for a Jackson tandem network
This paper considers importance sampling as a tool for rare-event simulation. The focus is on estimating the probability of overflow in the downstream queue of a Jacksonian two-n...
Denis I. Miretskiy, Werner R. W. Scheinhardt, Mich...