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ATAL
2010
Springer
15 years 7 months ago
Aggregating preferences in multi-issue domains by using maximum likelihood estimators
In this paper, we study a maximum likelihood estimation (MLE) approach to preference aggregation and voting when the set of alternatives has a multi-issue structure, and the voter...
Lirong Xia, Vincent Conitzer, Jérôme ...
BMCBI
2010
154views more  BMCBI 2010»
15 years 6 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
BMCBI
2007
157views more  BMCBI 2007»
15 years 6 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
BMCBI
2008
107views more  BMCBI 2008»
15 years 6 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...
CORR
2010
Springer
159views Education» more  CORR 2010»
15 years 6 months ago
Outlier Detection Using Nonconvex Penalized Regression
This paper studies the outlier detection problem from the point of view of penalized regressions. Our regression model adds one mean shift parameter for each of the n data points....
Yiyuan She, Art B. Owen