Background: In recent years, quartet-based phylogeny reconstruction methods have received considerable attentions in the computational biology community. Traditionally, the accura...
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
We describe the informatics requirements of translational biomedical research projects and how e-Science tools can be used to address them. We use pattern templates to describe the...
maintain awareness of its environment for a long period of time. Additionally, knowledge-intensive agents must be engineered such that their knowledge can be easily updated as envi...