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BMCBI
2007
122views more  BMCBI 2007»
15 years 6 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2007
138views more  BMCBI 2007»
15 years 6 months ago
A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
Background: A key challenge in metabonomics is to uncover quantitative associations between multidimensional spectroscopic data and biochemical measures used for disease risk asse...
Aki Vehtari, Ville-Petteri Mäkinen, Pasi Soin...
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...
ESE
2006
154views Database» more  ESE 2006»
15 years 6 months ago
Prioritizing JUnit Test Cases: An Empirical Assessment and Cost-Benefits Analysis
Test case prioritization provides a way to run test cases with the highest priority earliest. Numerous empirical studies have shown that prioritization can improve a test suite�...
Hyunsook Do, Gregg Rothermel, Alex Kinneer
BMCBI
2007
139views more  BMCBI 2007»
15 years 6 months ago
Significance analysis of microarray transcript levels in time series experiments
Background: Microarray time series studies are essential to understand the dynamics of molecular events. In order to limit the analysis to those genes that change expression over ...
Barbara Di Camillo, Gianna Toffolo, Sreekumaran K....
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