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166
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BMCBI
2006
15 years 6 months ago
2006
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
169
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BMCBI
2006
15 years 6 months ago
2006
Background: Due to the large number of genes in a typical microarray dataset, feature selection looks set to play an important role in reducing noise and computational cost in gen...
168
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BMCBI
2006
15 years 6 months ago
2006
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
204
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BMCBI
2006
15 years 6 months ago
2006
Background: Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the Nomenclat...
148
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BMCBI
2006
15 years 6 months ago
2006
Background: Frequently, several alternative names are in use for biological objects such as genes and proteins. Applications like manual literature search, automated text-mining, ...