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BMCBI
2008
102views more  BMCBI 2008»
15 years 6 months ago
Monitoring the evolutionary aspect of the Gene Ontology to enhance predictability and usability
Background: Much effort is currently made to develop the Gene Ontology (GO). Due to the dynamic nature of information it addresses, GO undergoes constant updates whose results are...
Jong C. Park, Tak-eun Kim, Jinah Park
BMCBI
2008
185views more  BMCBI 2008»
15 years 6 months ago
Mining clinical relationships from patient narratives
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
Angus Roberts, Robert J. Gaizauskas, Mark Hepple, ...
BMCBI
2008
99views more  BMCBI 2008»
15 years 6 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
BMCBI
2008
132views more  BMCBI 2008»
15 years 6 months ago
Very Important Pool (VIP) genes - an application for microarray-based molecular signatures
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
BMCBI
2008
106views more  BMCBI 2008»
15 years 6 months ago
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology
Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity an...
Mikel Egaña Aranguren, Erick Antezana, Mart...
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