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173
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BMCBI
2008
15 years 6 months ago
2008
Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
148
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BMCBI
2008
15 years 6 months ago
2008
Background: There has been recent concern regarding the inability of predictive modeling approaches to generalize to new data. Some of the problems can be attributed to improper m...
184
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BMCBI
2008
15 years 6 months ago
2008
Background: Despite increasing interest in applying Natural Language Processing (NLP) to biomedical text, whether this technology can facilitate tasks such as database curation re...
183
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BMCBI
2008
15 years 6 months ago
2008
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
174
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BMCBI
2008
15 years 6 months ago
2008
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...