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151
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BMCBI
2008
15 years 6 months ago
2008
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
158
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BMCBI
2008
15 years 6 months ago
2008
Background: DNA microarray technology has emerged as a major tool for exploring cancer biology and solving clinical issues. Predicting a patient's response to chemotherapy is...
146
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BMCBI
2008
15 years 6 months ago
2008
Background: We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR) contro...
156
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BMCBI
2008
15 years 6 months ago
2008
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
201
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BMCBI
2008
15 years 6 months ago
2008
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...