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BMCBI
2007
99views more  BMCBI 2007»
15 years 6 months ago
Stratification bias in low signal microarray studies
Background: When analysing microarray and other small sample size biological datasets, care is needed to avoid various biases. We analyse a form of bias, stratification bias, that...
Brian J. Parker, Simon Günter, Justin Bedo
BMCBI
2008
163views more  BMCBI 2008»
15 years 6 months ago
The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology
Background: High-throughput genome biological experiments yield large and multifaceted datasets that require flexible and user-friendly analysis tools to facilitate their interpre...
Frédéric Chalmel, Michael Primig
BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2007
152views more  BMCBI 2007»
15 years 6 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim
BMCBI
2007
105views more  BMCBI 2007»
15 years 6 months ago
Predicting RNA secondary structure by the comparative approach: how to select the homologous sequences
Background: The secondary structure of an RNA must be known before the relationship between its structure and function can be determined. One way to predict the secondary structur...
Stefan Engelen, Fariza Tahi
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