Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...