11752 search results - page 2161 / 2351 » Those |
161
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BMCBI
2007
15 years 6 months ago
2007
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
168
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BMCBI
2008
15 years 6 months ago
2008
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
148
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BMCBI
2010
15 years 6 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
188
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BMCBI
2008
15 years 6 months ago
2008
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
146
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BMCBI
2008
15 years 6 months ago
2008
Background: Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positiv...