11752 search results - page 2159 / 2351 » Those |
161
click to vote
BMCBI
2007
15 years 6 months ago
2007
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
151
click to vote
BMCBI
2007
15 years 6 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
155
click to vote
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
15 years 6 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
161
click to vote
BMCBI
2008
15 years 6 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
194
click to vote
BMCBI
2008
15 years 6 months ago
2008
Background: Recent discoveries of a large variety of important roles for non-coding RNAs (ncRNAs) have been reported by numerous researchers. In order to analyze ncRNAs by kernel ...