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BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
BMCBI
2007
123views more  BMCBI 2007»
15 years 6 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2007
153views more  BMCBI 2007»
15 years 6 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
BMCBI
2008
140views more  BMCBI 2008»
15 years 6 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
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