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194
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BIB
2010
15 years 6 months ago
2010
PathwayTools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates ...
181
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BMCBI
2010
15 years 6 months ago
2010
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
157
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BMCBI
2010
15 years 6 months ago
2010
Background: In HIV treatment it is critical to have up-to-date resistance data of applicable drugs since HIV has a very high rate of mutation. These data are made available throug...
183
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BMCBI
2010
15 years 6 months ago
2010
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
181
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BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
15 years 6 months ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...