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BMCBI
2007
113views more  BMCBI 2007»
15 years 6 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
PR
2008
218views more  PR 2008»
15 years 6 months ago
Automatic feature localisation with constrained local models
We present an efficient and robust method of locating a set of feature points in an object of interest. From a training set we construct a joint model of the appearance of each fe...
David Cristinacce, Timothy F. Cootes
INTERNET
2007
182views more  INTERNET 2007»
15 years 6 months ago
Analysis of Caching and Replication Strategies for Web Applications
Replication and caching mechanisms are often employed to enhance the performance of Web applications. In this article, we present a qualitative and quantitative analysis of state-...
Swaminathan Sivasubramanian, Guillaume Pierre, Maa...
BMCBI
2004
174views more  BMCBI 2004»
15 years 6 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
EVOW
2010
Springer
15 years 4 months ago
Finding Gapped Motifs by a Novel Evolutionary Algorithm
Background: Identifying approximately repeated patterns, or motifs, in DNA sequences from a set of co-regulated genes is an important step towards deciphering the complex gene reg...
Chengwei Lei, Jianhua Ruan