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BMCBI
2008
135views more  BMCBI 2008»
15 years 6 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
BMCBI
2008
142views more  BMCBI 2008»
15 years 6 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...
BMCBI
2006
161views more  BMCBI 2006»
15 years 6 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
IOR
2007
65views more  IOR 2007»
15 years 6 months ago
A Comparison of the Optimal Costs of Two Canonical Inventory Systems
We compare two inventory systems, one in which excess demand is lost and the other in which excess demand is backordered. Both systems are reviewed periodically. They experience t...
Ganesh Janakiraman, Sridhar Seshadri, J. George Sh...
PAMI
1998
84views more  PAMI 1998»
15 years 6 months ago
Intrinsic Dimensionality Estimation With Optimally Topology Preserving Maps
A new method for analyzing the intrinsic dimensionality (ID) of low dimensional manifolds in high dimensional feature spaces is presented. The basic idea is to rst extract a low-d...
Jörg Bruske, Gerald Sommer