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» The evolutionary capacity of protein structures
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BMCBI
2008
175views more  BMCBI 2008»
15 years 6 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
ICASSP
2007
IEEE
16 years 8 days ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
BMCBI
2010
137views more  BMCBI 2010»
15 years 29 days ago
The ancient history of the structure of ribonuclease P and the early origins of Archaea
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
Feng-Jie Sun, Gustavo Caetano-Anollés
JCB
2000
101views more  JCB 2000»
15 years 5 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...
CBMS
2009
IEEE
16 years 23 days ago
On the storage, management and analysis of (multi) similarity for large scale protein structure datasets in the grid
Assessment of the (Multi) Similarity among a set of protein structures is achieved through an ensemble of protein structure comparison methods/algorithms. This leads to the genera...
Gianluigi Folino, Azhar Ali Shah, Natalio Krasnogo...