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190
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BMCBI
2010
15 years 7 months ago
2010
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
182
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BMCBI
2010
15 years 7 months ago
2010
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
159
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BMCBI
2010
15 years 7 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
201
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BMCBI
2008
15 years 7 months ago
2008
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
173
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BMCBI
2007
15 years 7 months ago
2007
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...