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» The complexity of stochastic sequences
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BMCBI
2010
102views more  BMCBI 2010»
15 years 6 months ago
Alignment and clustering of phylogenetic markers - implications for microbial diversity studies
Background: Molecular studies of microbial diversity have provided many insights into the bacterial communities inhabiting the human body and the environment. A common first step ...
James Robert White, Saket Navlakha, Niranjan Nagar...
BMCBI
2007
162views more  BMCBI 2007»
15 years 6 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2008
105views more  BMCBI 2008»
15 years 6 months ago
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania
Background: Leishmania and other members of the Trypanosomatidae family diverged early on in eukaryotic evolution and consequently display unique cellular properties. Their appare...
Martin Smith, Mathieu Blanchette, Barbara Papadopo...
BMCBI
2008
158views more  BMCBI 2008»
15 years 6 months ago
Bioinformatics in Italy: BITS2007, the fourth annual meeting of the Italian Society of Bioinformatics
spectives. A total of 149 abstracts were accepted and presented in the poster session and 31 of them were selected for oral presentation. At the opening of the meeting, Roderic Gui...
Graziano Pesole, Manuela Helmer-Citterich
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...