5668 search results - page 790 / 1134 » The case for software evolution |
161
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BMCBI
2006
15 years 6 months ago
2006
Background: The neighbor-joining method by Saitou and Nei is a widely used method for constructing phylogenetic trees. The formulation of the method gives rise to a canonical (n3)...
203
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BMCBI
2006
15 years 6 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
205
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BMCBI
2006
15 years 6 months ago
2006
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
191
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BMCBI
2006
15 years 6 months ago
2006
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
185
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BMCBI
2007
15 years 6 months ago
2007
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...