A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
The formalism of probabilistic graphical models provides a unifying framework for capturing complex dependencies among random variables, and building large-scale multivariate stat...
This paper presents several Arcs-States models that can be applied to numerous vehicle routing problems, one of which is the well-known vehicle routing problem with capacities and...
Model transformation has become one of the most focused research field, motivated by for instance the OMG's Model-Driven Architecture (MDA). Metamodeling is a central techniq...
A concurrent engineering-oriented design database representation model (CE-DDRM) is introduced in this research for supporting various life-cycle aspects in concurrent design. In ...