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BMCBI
2010
130views more  BMCBI 2010»
15 years 7 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BMCBI
2007
109views more  BMCBI 2007»
15 years 7 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
BMCBI
2008
158views more  BMCBI 2008»
15 years 7 months ago
Discovering gene annotations in biomedical text databases
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...
Ali Cakmak, Gultekin Özsoyoglu
BMCBI
2008
130views more  BMCBI 2008»
15 years 7 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
BMCBI
2010
86views more  BMCBI 2010»
15 years 7 months ago
The oligodeoxynucleotide sequences corresponding to never-expressed peptide motifs are mainly located in the non-coding strand
Background: We study the usage of specific peptide platforms in protein composition. Using the pentapeptide as a unit of length, we find that in the universal proteome many pentap...
Giovanni Capone, Giuseppe Novello, Candida Fasano,...
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