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BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen
BMCBI
2008
139views more  BMCBI 2008»
15 years 6 months ago
New challenges for text mining: mapping between text and manually curated pathways
Background: Associating literature with pathways poses new challenges to the Text Mining (TM) community. There are three main challenges to this task: (1) the identification of th...
Kanae Oda, Jin-Dong Kim, Tomoko Ohta, Daisuke Okan...
BMCBI
2005
132views more  BMCBI 2005»
15 years 6 months ago
CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...
BMCBI
2007
104views more  BMCBI 2007»
15 years 6 months ago
Joint mapping of genes and conditions via multidimensional unfolding analysis
Background: Microarray compendia profile the expression of genes in a number of experimental conditions. Such data compendia are useful not only to group genes and conditions base...
Katrijn Van Deun, Kathleen Marchal, Willem J. Heis...
BMCBI
2008
105views more  BMCBI 2008»
15 years 6 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...