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BMCBI
2010
109views more  BMCBI 2010»
15 years 7 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi
BMCBI
2004
114views more  BMCBI 2004»
15 years 6 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
QRE
2010
129views more  QRE 2010»
15 years 5 months ago
Improving quality of prediction in highly dynamic environments using approximate dynamic programming
In many applications, decision making under uncertainty often involves two steps- prediction of a certain quality parameter or indicator of the system under study and the subseque...
Rajesh Ganesan, Poornima Balakrishna, Lance Sherry
BMCBI
2011
15 years 1 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...