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» The Predictability of Data Values
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BMCBI
2007
107views more  BMCBI 2007»
15 years 6 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
BMCBI
2008
116views more  BMCBI 2008»
15 years 6 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
BMCBI
2011
15 years 1 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
ICMLA
2008
15 years 8 months ago
A Clustering Approach in Developing Prognostic Systems of Cancer Patients
Accurate prediction of survival rates of cancer patients is often key to stratify patients for prognosis and treatment. Survival prediction is often accomplished by the TNM system...
Dechang Chen, Kai Xing, Donald Henson, Li Sheng, A...
RECOMB
2009
Springer
16 years 7 months ago
Learning Models for Aligning Protein Sequences with Predicted Secondary Structure
Accurately aligning distant protein sequences is notoriously difficult. A recent approach to improving alignment accuracy is to use additional information such as predicted seconda...
Eagu Kim, Travis J. Wheeler, John D. Kececioglu