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BMCBI
2010
114views more  BMCBI 2010»
15 years 6 months ago
Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray develop
Background: Microorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic poten...
Sébastien Terrat, Eric Peyretaillade, Olivi...
ISCA
2000
IEEE
156views Hardware» more  ISCA 2000»
15 years 11 months ago
CHIMAERA: a high-performance architecture with a tightly-coupled reconfigurable functional unit
Reconfigurable hardware has the potential for significant performance improvements by providing support for application−specific operations. We report our experience with Chimae...
Zhi Alex Ye, Andreas Moshovos, Scott Hauck, Prithv...
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2007
157views more  BMCBI 2007»
15 years 6 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
AINA
2007
IEEE
16 years 1 months ago
Cost-Function-Based Network Selection Strategy in Integrated Wireless and Mobile Networks
—Wireless and mobile networks have experienced great success over the past few years. However, any single type of wireless and mobile network cannot provide all types of services...
Wei Shen, Qing-An Zeng