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BMCBI
2008
84views more  BMCBI 2008»
15 years 7 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2006
149views more  BMCBI 2006»
15 years 6 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2006
169views more  BMCBI 2006»
15 years 6 months ago
Machine learning techniques in disease forecasting: a case study on rice blast prediction
Background: Diverse modeling approaches viz. neural networks and multiple regression have been followed to date for disease prediction in plant populations. However, due to their ...
Rakesh Kaundal, Amar S. Kapoor, Gajendra P. S. Rag...
DSS
2006
184views more  DSS 2006»
15 years 6 months ago
Building a scientific knowledge web portal: The NanoPort experience
There has been a tremendous growth in the amount of information and resources on the World Wide Web that are useful to researchers and practitioners in science domains. While the ...
Michael Chau, Zan Huang, Jialun Qin, Yilu Zhou, Hs...
BMCBI
2007
180views more  BMCBI 2007»
15 years 6 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
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