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BMCBI
2010
112views more  BMCBI 2010»
15 years 7 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
BMCBI
2010
150views more  BMCBI 2010»
15 years 7 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2010
132views more  BMCBI 2010»
15 years 7 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
CN
2008
117views more  CN 2008»
15 years 7 months ago
Broker-placement in latency-aware peer-to-peer networks
In large peer-to-peer (P2P) overlay networks, nodes usually share resources to support all kinds of applications. In such networks, a subset of the nodes may assume the role of br...
Pawel Garbacki, Dick H. J. Epema, Maarten van Stee...
BMCBI
2006
139views more  BMCBI 2006»
15 years 7 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
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