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SIGCOMM
2010
ACM
15 years 6 months ago
Topology-aware resource allocation for data-intensive workloads
This paper proposes an architecture for optimized resource allocation in Infrastructure-as-a-Service (IaaS)-based cloud systems. Current IaaS systems are usually unaware of the ho...
Gunho Lee, Niraj Tolia, Parthasarathy Ranganathan,...
GECCO
2010
Springer
244views Optimization» more  GECCO 2010»
15 years 6 months ago
Implicit fitness and heterogeneous preferences in the genetic algorithm
This paper takes an economic approach to derive an evolutionary learning model based entirely on the endogenous employment of genetic operators in the service of self-interested a...
Justin T. H. Smith
BMCBI
2008
200views more  BMCBI 2008»
15 years 6 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2010
139views more  BMCBI 2010»
15 years 6 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2007
165views more  BMCBI 2007»
15 years 6 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
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