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BMCBI
2010
162views more  BMCBI 2010»
15 years 6 months ago
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang, Che...
BMCBI
2008
145views more  BMCBI 2008»
15 years 6 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
116views more  BMCBI 2008»
15 years 6 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
BMCBI
2008
125views more  BMCBI 2008»
15 years 6 months ago
Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors
Background: The Potato type II (Pot II) family of proteinase inhibitors plays critical roles in the defense system of plants from Solanaceae family against pests. To better unders...
Lesheng Kong, Shoba Ranganathan
CORR
2006
Springer
103views Education» more  CORR 2006»
15 years 6 months ago
AS Relationships: Inference and Validation
Research on performance, robustness, and evolution of the global Internet is fundamentally handicapped without accurate and thorough knowledge of the nature and structure of the c...
Xenofontas A. Dimitropoulos, Dmitri V. Krioukov, M...
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