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162
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BMCBI
2010
15 years 6 months ago
2010
Background: Metagenomics is the study of environmental samples using sequencing. Rapid advances in sequencing technology are fueling a vast increase in the number and scope of met...
175
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BMCBI
2010
15 years 6 months ago
2010
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
136
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BMCBI
2008
15 years 6 months ago
2008
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
148
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BMCBI
2010
15 years 6 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
179
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BMCBI
2007
15 years 6 months ago
2007
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....